The Substance
If you follow the instructions, what could go wrong?
7.3
282 votes
Release07 Sep, 2024
Runtime141 min
Budget $17,500,000.00
Revenue $16,846,463.00
- Horror
- Drama
- Science Fiction
STORY
A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
TRAILERS
Official Clip - Lucky Day
Official Clip - Pump It Up With Sue
Breaking Down THE SUBSTANCE's Shrimp Scene
The hype is real
TIFF 2024 Q&A
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Official Trailer
Official Teaser
Official Clip
CAST
Demi Moore
Elisabeth Sparkle
Margaret Qualley
Sue
Dennis Quaid
Harvey
Edward Hamilton-Clark
Fred
Gore Abrams
Oliver
Christian Erickson
Man at Diner
Robin Greer
Male Nurse
Hugo Diego Garcia
Diego
Olivier Raynal
Alan
Tiffany Hofstetter
The Stylist
Tom Morton
The Doctor
Jiselle Burkhalter
Girl
Axel Baille
The Photographer
Oscar Lesage
Troy
Matthew Géczy
Bob Haswell
Philip Schurer
Mr. Scream
Daniel Knight
Casting Director
Namory Bakayoko
Silhouette
Bill Bentley
Suit
Lucie Laffin
Woman from the Public
Gregory Defleur
Happy Birthday Person
Vincent Colombe
Suit
Yann Bean
“The Substance” (voice)